Mesna is an indispensable supportive care therapy for detoxification of urotoxic metabolites of ifosfamide and cyclophosphamide (when given in high dose).

Mesna is an indispensable supportive care therapy for detoxification of urotoxic metabolites of ifosfamide and cyclophosphamide (when given in high dose). The dose of Mesna is atleast 20% of the ifosfamide dose on a mg-weight basis and is administered just prior to, or mixed with, ifosfamide dose. It is again given after 4 hours and after 8 hours after the ifosfamide dose. Thus, Mesna is provided in a combipack along with ifosfamide. Mesna is also available separately.

 

Indications:

  • Use for prophylaxis of ifosfamide- induced haemorrhagic cystitis.
  • To prevent or reduce haemorrhagic cystitis associated with high dose cyclophosphamide therapy.

 

Generic Name

Strength

Standard

Type

Packing

Pack Size

Mesna

200 mg

IHS

INJ

Amp

2 ml