Clotrimazole is a broad-spectrum azole antifungal agent that inhibits the growth of pathogenic yeasts by altering the permeability of cell membranes.

Clotrimazole is a broad-spectrum azole antifungal agent that inhibits the growth of pathogenic yeasts by altering the permeability of cell membranes. It is only approved for the treatment of fungal infections of the mouth or throat. It may also be used to prevent these infections in patients receiving treatments that may weaken the body’s immune system (e.g., chemotherapy). The action of clotrimazole is fungistatic at higher concentration and may be fungicidal in vitro against Candida albicans and other species of the genus Candida.

 

Indications

  • Indicates for prophylactically to reduce the incidence of oropharyngeal candidiasis in patients immunocompromised by conditions that include chemotherapy, radiotherapy, or steroid therapy utilized in the treatment of leukemia, solid tumors, or renal transplantation.

Generic Name

Strength

Standard

Type

Packing

Pack Size

Clotrimazole Lozenges

10 mg

USP

Tablet

Strip

1 X 10